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Couple of days ago I was juggling through some books and magazines and found an article on a new discipline – Nucleopathy, for the treatment of virtually untreatable, intractable and hopeless medical conditions.

Honestly this was inspiring and something new to me; which fomented me to share.

This was an interview of Prof Dr. Shahid H. Sheikh — MBBS, MD, PhD*, FACPE (USA), and MISID (USA), A Neurologist.

Dr. Shahid is running an institute namely NIDS Treatment & Research Center, Pakistan. He claims to have successfully treated many hopeless cases including two children with Cerebral Palsy (CP).

This interview has been recently published in an Urdu magazine and I am translating it for Pharma Veterans with the objective to disseminate new researches and developments as much as possible, not only for academic purpose but also as a ray of hope. The idea of sharing it is that those who feel helpless with some incurable ailments and have lost hope may get the benefit from this mode of treatment. However, I do not want to judge myself too authentic and suggest that before trying it out, one should find more details about its veracity.

Here I am reproducing an article of Dr. Shahid, published in BJSTR, introducing the concept.


Conventionally, the understanding of any given human ailment aligns with system to organ to tissues, membranes and cells. We call it “Cytopathology”, we engage in a variety of diagnostic tools to evidence such Cytopathology to confirm our diagnoses and tailor a medical or surgical plan according to the given established protocols.

Atomic Force Microscopy (AFM) has brought a new paradigm in the view to best clear our understanding of the emerging pathophysiology of a given symptomatic pathology. No more we can logically treat a disease based on the symptomatic realm of outdated guidelines, adhering to “Etiology Unknown”. Today, majority of the ailments have only symptomatic relief/ treatment.

There is an urgency to take a deeper look at the source of ailments and try to define the possible etiology for a better, comprehensive and a permanent relief to the ailing humanity. Nucleus of a given cell being the controlling entity for that cell’s homeostasis, its timely development and its functions, so is true of the controlling Neurons of the Brain.

In 2004, Late Dr. Edward Wagoner and his team at the University of California at Irvine did not fathom the idea that they were about to change a paradigm of etiology. His team Dr. Alex Malkin, Dr. Alex McPhearson and Dr. Marco Plomp used the AFM and revealed the real time “Nano-Pathological” series of events that Dr. Wagoner reported in his last publication. I was fortunate to have this opportunity to evaluate their findings clinically and integrate into the clinical practice to best diagnose and help alleviate the symptoms and neo-pathogenesis, that help prevail the homeostasis of cells, tissues, organs, system that promote the quality of life.

Cytopathology is no longer an absolute reliable tool to finalize the proper diagnoses. Currently, so called treatments are merely a symptomatic pacification to borrow time for the resident immune system to re-congregate/ revitalize against the pathogens in question. The Nucleopathology of the controlling neurons indeed is the paradigm shift, the grass root Instigator of the basic symptomatology that results into the disruption of the normal homeostasis.

However, pacifying the symptoms is not the final treatment of the chronic ailment. On the contrary it is the opportunity given to the pathophysiology to continue to grow into a bigger challenge, eventually becoming an incurable disease.

To date, this phenomenon has been a hidden secret of nature. Now that is opened, it is unraveling the possible etiologies of the unknown nature of the conventional diseases, mentioned in the table below. The “Sheikh’s Syndrome” is rightfully a very well established guideline to see any disease’s root cause etiology and possible treatment to eradicate the ailment.


                                                Diseases Linked to the Nucleopathy


ADD (Attention Deficit Disorder) *Allergies *Alzheimer
Amenorrhea *Anemia *Aneurysms
Atherosclerosis *Asthma *Bell’s & Cerebral Palsy
CAD (Coronary Artery Disease) *Cancer *CFS (Chronic Fatigue Syndrome)
Cognitive Disorder *Chromosomal Disorder *Diabetes Mellitus
Encephalitis *Endocrine Disorders *Gastroenteritis
Gastric Ulcer *Gynecomastia *Hypertension
Hypohemoglobinemia *Hyperlipidemia *Hypothalamic Dysfunction
Hypo/ hyperthyroidism *Impotence *Infertility
IBS (Irritable Bowel Syndrome) *Liver Dysfunction  *Meningitis
Metabolic Disorder *M.S.(Multiple Sclerosis) *Neoplastic-Tumors
Neuralgia *Neuropathy *Nephropathy
Parkinson’s *Psychiatric disorders *Pituitary Dysfunctions
Recurrence of Minor Infections    
Sudden Tachycardia *Schizophrenia *Respiratory Failure
Stroke *Teenage Drug Addiction  



  1. Wagner EK (1999) Herpes Simplex Virus Molecular Biology. In Encyclopedia of Virology, (2nd Edn.). In: RG Webster, A. Granoff (Eds.). Academic Press, London, England, UK, pp. 686-697.2.
  2. Wagner EK, Garcia Ramirez, JJ Stingley, SW Aguilar, JS Buehler, et al. (2002) Practical Approaches to Long Oligonucleotide-Based DNA Microarray: Lessons From Herpes Viruses. Progress in Nucleic Acids Research 71: 445-492.3.
  3. The Sheikh’s Syndrome (2012) IOSR Journal of Dental and Medical Sciences 1(5).4. (2014)
  4. Neuro Invasive Viruses the Silent & Slow Killers February, 2014 IOSR Journal of Dental and Medical Sciences 13(3).
  5. Shahid Hussain Sheikh — Biomed J Sci & Tech Res Volume 4- Issue 4: 2018
  6. Biomedical Journal of Scientific & Technical Research (BJSTR)


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